Saturday, May 5, 2012

Pharmacology and Pharmacy Questions

Unit 1: Pharmacology and Pharmacy Questions 1. Define a drug. 2. Define: pharmacokinetics, pharmacodynamics and pharmacogenetics. 3. Explain the parenteral route of drug administration. 4. What are the different processes by which drugs are absorbed into the body? 5. Define pharmaceutically equivalent drugs and pharmaceutically bioequivalent drugs. 6. What are the physiological factors of patients that affect the absorption and bioavailability? 7. Write down a short note on drug storage in the body. 8. Write down a short note on plasma half life and its significance. 9. What is the fate of a drug after absorption? 10. What do you understand by special drug delivery systems? 11. What are the different mechanisms of drug action? 12. Differentiate adverse drug reaction and drug allergy. 13. Explain pharmacogenetics. 14. Classify antibiotics. 15. What do you understand by susceptibility and resistance of a microorganism to an antibiotic? What are the reasons for bacterial resistance? 16. In what conditions multiple antibiotic therapies are performed? What are the disadvantages? 17. Explain the possible negative outcomes of antimicrobial therapy. 18. What are the reasons behind failure of antimicrobial therapy? 19. Explain the misuse of antimicrobial therapy. 20. How can antibiotic resistance be avoided? 21. What are the general principles of prescribing? 22. Explain GI absorption of drugs in pediatric patients. 23. What are the points to be taken into account while prescribing for geriatric patients? 24. What are the points to be taken into account while prescribing in pregnancy? 25. What are the factors that affect placental transfer of drugs? 26. How can drugs be classified? 27. Explain the classification of drugs according to legal requirements. 3. Date of manufacture and expiry date of drugs, handling and drug storage. Concepts of GMP, GLP and GCP 28. Mention the importance of stability of drugs? 29. What do you mean by label? What kind of information that should be included in a label for a drug product? 30. Write down a short note on storage of drugs. 4. Basic concepts of rational drug use 31. What do you mean by rational use of drugs? Discuss the importance of rational use of drugs. 32. Point out the reasons for irrational use of drugs. 33. What are the disadvantages of irrational use of drugs? 34. How can rational use of drug be promoted? 8 35. Define standard treatment guidelines. Discuss the importance of standard treatment guidelines. 7 36. Mention the advantages and disadvantages of standard treatment guidelines. 37. Explain the process to establish standard treatment guidelines. 38. What are the key features for successful standard treatment guidelines? 39. Point out the elements to implement standard treatment guidelines. 40. What do you understand by life saving drugs? Discuss on side effects and contraindications of any two life saving drugs. 41. Definition, Characteristics, Types, Management/Drugs used, MoA of drugs, Adverse effects of the drugs, Contraindications and Drug interactions of drugs used in TB, malaria, Kala-azar, leprosy, ARI, Diarrheal diseases, common infections, HIV/AIDS, COPD, diabetes, Hypertension. 42. Define essential drug list and mention its importance. 43. Discuss the criteria for selecting essential drugs. 44. Short note on: Use of antibiotics in food and animals and public health. 45. Definition, 46. Short note: Importance of Drug Act. 47. Short note: National Drug Policy. 48. Differentiate innate immunity and acquired immunity. 49. Differentiate active immunity and passive immunity. 50. What are antibodies? 51. What are vaccines? 52. Explain the different types of vaccines? 53. Mention the importance of maintaining cold chain.

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